The Intersection of Functional Matrix Theory and Epigenetics in Craniofacial Development

Abstract

Craniofacial development—the growth of our skull and face—is influenced by a mix of genetics, environment, and how our bodies function. Melvin Moss's Functional Matrix Theory changed our understanding by suggesting that facial bones grow not just because of genetics but also due to the demands of nearby soft tissues like muscles and glands. This article explores the core ideas of this theory, its relevance today, and how it connects with epigenetics—the study of how environmental factors can change gene expression without altering DNA. By looking at how our environment affects gene activity, we gain insights into the dynamic processes that shape facial development. This understanding has important implications for personalized orthodontic care, helping professionals tailor treatments based on both genetic and environmental factors.

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