Mechanotransduction Part 3: Why Mewing Works

Abstract

Mewing, a technique involving the intentional positioning of the tongue against the roof of the mouth, has gained considerable attention for its potential benefits in enhancing facial aesthetics and promoting oral health. This review examines the underlying scientific mechanisms of mewing, particularly focusing on mechanotransduction and bone remodeling. Mechanotransduction, the process by which cells convert mechanical stimuli into biochemical signals, is a well-established factor in bone adaptation and remodeling. The sustained pressure from the tongue during mewing appears to influence craniofacial development through these biomechanical pathways. Additionally, mewing supports nasal breathing, improves dental alignment, and enhances postural stability. While direct studies on mewing are still emerging, the principles it relies on are grounded in solid scientific evidence. This article aims to provide a comprehensive understanding of the potential benefits of mewing, emphasizing its basis in well-documented physiological processes and its implications for facial development and oral health.

Introduction

Mewing, a term made by the community that follows Dr. John Mew and popularized by his son, Dr. Mike Mew, refers to a practice that emphasizes proper tongue posture to potentially influence facial development and improve oral health. Specifically, it involves maintaining the tongue in contact with the roof of the mouth, keeping the lips closed, and ensuring the teeth are lightly touching. This seemingly simple technique has sparked widespread interest and debate within both the scientific community and the general public.

The growing popularity of mewing is rooted in the belief that it can lead to a more defined jawline, improved dental alignment, and better overall facial aesthetics. Proponents argue that these benefits arise from fundamental physiological processes such as mechanotransduction and bone remodeling, which are well-documented in scientific literature. Importantly, these processes are not limited to children and adolescents. Adults can also experience benefits from mewing due to the continuous nature of bone remodeling and osteogenesis. Osteogenesis, the process of new bone formation, can induce changes at the DNA level, potentially leading to long-term structural changes in the facial bones even in adulthood.

However, despite the enthusiasm surrounding mewing, rigorous scientific investigations specifically targeting this practice are still limited. This article seeks to bridge the gap between anecdotal reports and scientific evidence by examining the underlying mechanisms that support mewing. By exploring how mechanotransduction and bone remodeling contribute to craniofacial development, we aim to provide a deeper understanding of why mewing may be effective. Additionally, we will discuss the broader implications of mewing for oral health and posture, highlighting the potential benefits that extend beyond mere aesthetics.

Mechanisms of Action

Mechanotransduction

Mechanotransduction is a critical and well-documented biological process where cells convert mechanical stimuli into biochemical signals, leading to various cellular responses. This process is integral to the adaptation and remodeling of bone. When considering mewing, the sustained pressure exerted by the tongue against the roof of the mouth generates mechanical forces that are transmitted to the maxillary (upper jaw) and mandibular (lower jaw) bones. These mechanical forces are detected by osteocytes, the primary mechanosensitive cells within bone tissue.

Osteocytes respond to mechanical loading by initiating signaling pathways that result in the release of signaling molecules such as prostaglandins and nitric oxide. These molecules influence the activity of osteoblasts (bone-forming cells) and osteoclasts (bone-resorbing cells), promoting bone remodeling and adaptation. This process is not only crucial for maintaining bone integrity but also for reshaping bone structure in response to mechanical demands. The scientific community widely recognizes mechanotransduction as a fundamental principle in bone biology, with extensive research supporting its role in bone formation and maintenance.

Bone Remodeling

Bone remodeling is a dynamic and continuous process involving the coordinated activity of osteoblasts and osteoclasts. This process allows bones to adapt to mechanical stresses and repair microdamage. The mechanical forces generated by proper tongue posture during mewing can enhance osteoblastic activity, leading to increased bone formation, while also modulating osteoclastic activity to resorb bone where necessary.

The remodeling process involves several stages:

  1. Activation: Mechanical loading stimulates osteocytes, which release signaling molecules to recruit osteoclasts to the bone surface.
  2. Resorption: Osteoclasts create an acidic environment that dissolves the mineral matrix of bone, forming resorption pits.
  3. Reversal: Mononuclear cells prepare the resorbed surface for new bone formation.
  4. Formation: Osteoblasts synthesize new bone matrix, which is subsequently mineralized to form new bone tissue.

Studies in orthodontics and orthopedics have demonstrated that mechanical loading, such as that applied during mewing, can significantly stimulate bone growth and adaptation. For instance, orthodontic treatments that apply consistent pressure to teeth can induce bone remodeling, leading to changes in tooth position and jaw structure. Similarly, physical therapies that apply mechanical forces to bones can enhance fracture healing and bone density.

Osteogenesis and Genetic Influence

Osteogenesis, the process of new bone formation, is intricately linked to mechanical stimuli and can lead to changes at the genetic level. Mechanical loading can induce the expression of genes associated with bone formation and remodeling, such as those encoding for collagen, bone morphogenetic proteins (BMPs), and other growth factors. These genetic responses facilitate long-term structural changes in bone tissue, supporting the efficacy of mewing for individuals of all ages.

Research has shown that mechanical forces can influence gene expression through several mechanisms:

  1. Mechanical Activation of Signaling Pathways: Mechanical forces can activate signaling pathways, such as the Wnt/β-catenin pathway, which are crucial for bone formation and remodeling.
  2. Epigenetic Modifications: Mechanical stimuli can lead to epigenetic changes, such as DNA methylation and histone modification, which regulate gene expression.
  3. Stem Cell Differentiation: Mechanical loading can influence the differentiation of mesenchymal stem cells into osteoblasts, promoting bone formation.

These mechanisms highlight the potential for mewing to induce structural changes in the facial bones, even in adulthood. The continuous nature of osteogenesis means that bone tissue remains responsive to mechanical stimuli throughout life, allowing for remodeling and adaptation in response to proper tongue posture.

Clinical Implications

The robust scientific basis provided by mechanotransduction, bone remodeling, and osteogenesis underscores the potential benefits of mewing. By maintaining proper tongue posture, individuals can stimulate these well-established physiological mechanisms, promoting favorable changes in facial structure and dental alignment. The genetic changes associated with osteogenesis further suggest that the benefits of mewing can extend into adulthood, offering a non-invasive method for enhancing facial aesthetics and oral health.

Conclusion

Mewing, grounded in well-established scientific principles like mechanotransduction, bone remodeling, and osteogenesis, shows potential for influencing facial structure and oral health. By promoting proper tongue posture, mewing leverages these physiological mechanisms to induce structural changes, even in adults. Although further research is needed to validate its efficacy fully, the theoretical basis suggests mewing could serve as a non-invasive method for enhancing facial aesthetics and dental alignment.

References

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